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2008 Published Scientific Studies by Dr. Loren Pickart

WHS POSTER 2008


Published Article to be presented in the J. Biomater, Sci. Polymer Edit. Vol 19, No. 8 pp. 969-988 (2008). For copyright reasons the full article is not available as yet. When it can be purchased from the publisher this page will be updated.

Review Paper 2008

More Published Studies on Tissue Remodeling Copper-Peptides


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Skin Biology Methods
For Scar Reduction

Products based on Integrity and True Science™


Hard Science for Scarless Skin

Using the Skin Remodeling System

 

How would you like to put a hex on vexing blemishes and pesky lesions? And how about zapping out nasty skin tags, scars, moles and more? Two Skin Remodeling Copper Peptide (SRCP) products – Super Cop and Super CP Serum – are enhanced with hydroxy acids, to reduce scars as they clarify the skin.

Dr. Pickart's discovered the system that remodels skin, that is, the process that removes scars and blemishes from your skin. His earlier inventions are used for cosmetic skin renewal, wound healing, hair growth and transplantation, and more. See new publications to the left.

Be warned that there is huge resistance to the ideas presented here even though they are supported by published research from over 40 laboratories. The field of dermatology has little interest in hard science and prefers a mindless, anti-science, gimmick-of-the-day approach to scar treatment.

These dynamic products are Dr. Loren Pickart's latest inventions that strongly remodel skin. They are designed to have a selective uptake into scars and lesions leading over time to beautiful, healthy, "remodeled" skin. We recommend that you start slowly in order for your skin to adjust.

Apply the products in the evening and rinse off the following morning with warm water to make sure all residue is removed.

Product Reviews: "I have a few old childhood scars on my body that have responded well to whatever CP product [SRCPs] I use on them. I recently had a deep gash on my hand that is barely noticeable after treating the healing scar with Copper-Peptides." (O.L.) Read more reviews...

 

 

Better Healing of Skin After Lasers, Peels, and Dermabrasion
Better Results with Chemical Skin Peels
Reduction of Acne Scars
Skin Tags
Sun Damage and Sun Damage Marks
Stretch Marks
General Scars, Skin Blemishes, Moles
Reduction of Acne with Copper Peptides
Super Cop and Super CP Serum
Dermatologists, Estheticians, Cosmetologists, Skin & Hair Care Stores, Bulk Prices of Products

 

 

 

 

 

Additional Information on this Page:
Scar Reduction with Strong Copper Peptides and Hydroxy Acids
If This Does Not Work Well Enough For You
Which Products to Order for Scar Reduction?
Compare Scar and Lesion Reduction Methods
Metalloproteinase Activation for Scar Removal
Copper Peptides Reduce the Scar-Producing Factor, TGF-beta
Technical Information
Product Ingredients
Copper Safety & Degenerative Disease Reduction
Return Policy
References

 

READ TESTIMONIALS ON SCAR REDUCTION USING SRCPS!

Safe, Natural, Scientific Products to
Help Reduce Acne Scars, Skin Scars, Skin Tags,
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Help Healing after Deep Peels, Laser Resurfacing,
and Dermabrasion

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SEBUM BE GONE (Oil Reduction Serum)

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Product

Price From
Order
Scar Reduction Test Kit
Helps determine which serums or creams are best for your skin. 
Contains 1 oz. Super CP Serum, 5ml LacSal Serum
1/4 oz. Super Cop 2X - Extra Strength, 1/4 oz. Exfol Cream
$30.95
TriReduction with Retinol  (2 oz or 4oz)
 $27.95
Exfol Cream - 2% Hydroxy Acid (2oz or 4oz)
$14.95
LacSal Cream - 10% Hydroxy Acid (1.7 oz)
$17.95
TriReduction Combo (Small or Large):
TriReduction plus an Exfoliating Cream of Your Choice!
Choose with either Exfol Cream or LacSal Cream
$36.95
Super Cop (0.5, 2 or 4 oz)
The strongest SRCP cream tested in human studies at UCSF. For spot use only.  Helps produce very strong skin repair but can be irritating. Do not over use. 
$29.95
Super Cop 2X - Extra Strength (0.5, 2 or 4 oz)
The strongest SRCP cream tested in human studies at UCSF. For spot use only.  Helps produce very strong skin repair but can be irritating. Do not over use. 
$45.95
Retinol in Squalane - 1 oz. 
Helps reduce scars but Retinol can cause breakouts in acne prone areas. So be sure to avoid areas prone to breakouts. 
$19.95
CP Serum
1 or 4 oz. bottle 
$22.95
Super CP Serum
1 or 4 oz. bottle 
$24.95
Exfol Serum - 2% Hydroxy Acid
1 or 4 oz. bottle  
$11.00
LacSal Serum - 10% Hydroxy Acid (1.7 oz)
$17.95
ORDER PRODUCT COMBOS
Choose from CP Serum or Super CP Serum + an Exfoliator of your choice!
$29.95
Emu Oil S Lipid Replenisher for Skin
Peroxide free emu oil supplemented with ubiquinone, leutin, lycopene, and mixed natural tocotrienols. To replenish depleted skin lipids in very dry or damaged skin. 2 oz.
$29.95

 



Fight Acne with a Vengeance – Enhance Copper Peptides with Hydroxy Acids and Defeat your Blemished Foes 

What do you suppose happens when hydroxy acids merge with strong remodeling copper peptides? The powerful duo creates a potent synergy to eradicate scars and blemishes with a surprising intensity. Compared to conventional methods for scar reduction which are costly, painful and only marginally effective, this method costs little and is painless.

Hydroxy acids, such as salicylic and glycolic acid, are widely used to exfoliate and peel skin. These acids remove dead cells while loosening and dissolving lesions such as acne scars, keloid scars, surgical scars, burn scars, moles, skin tags, stretch marks, age spots, and sun damage marks.

Here is the beauty of hydroxy acid actions: Your normal healthy skin resists these acids without any harm. However, most lesions, which have less structural integrity, are more easily broken down by hydroxy acids. The secret is to apply light acids over periods of a month or longer to slowly dissolve most lesions. This gentle approach is a pain free modification of normal skin peel techniques where strong and often harsh hydroxy acids (or other peeling agents such as TCA or phenol) are applied. These methods may work well under perfect circumstances. However, harsh hydroxy acids can inflame, especially when the skin does not regenerate or fully heal. When the dermis cannot rebuild, the peeling agent may cause scarring or inflammation.

When you use strong skin remodeling copper peptides (SRCPs) following the hydroxy acids, the peptides create an environment to regenerate normal healthy skin. So, as repeated applications of hydroxy acid dissolve away blemishes, SRCPs aid to rebuild a smooth and healthy complexion. By repeating this process once or twice daily, you should observe a noticeable improvement within a month.

Abrade Away those Acne Scars

You can scrape away unsightly scars with microdermabrasion and subcision (needling) that gently abrade the skin. These methods speed scar reduction in concert with SRCPs and hydroxy acids. When old scars grow course and tough, abrasive techniques allow hydroxy acids to dissolve the lesions. Microdermabrasion is most effective for elevated or flat scars. Subcision, used by estheticians, works better for depressed or pitted acne scars. The needling breaks up the deeply buried tissue. So go ahead - abrade those scars away to reveal a radient complexion.

Skin Remodeling – The Key to Scar Reduction

The key to unveiling a bright clear complexion depends on remodeling. This rebuilding process removes scars, lesions and stretch marks. Our skin is designed to heal wounds quickly to prevent blood loss and infection. Scars are manufactured from a rapidly formed "collagen glue" that the body deposits into an injured area for protection and strength. In ideal healing, wounds close rapidly after which the recovered area slowly rebuilds. This remodeling process removes collagen scars as it blends the area into nearby skin. What emerges is a healthy mixture of skin cells and invisible collagen fibers that replace the scars. Remodeling may continue in adults for ten years. However, the remodeling rate in children is high and their scars are rapidly removed. When we age, the rate diminishes and small scars may remain for years. As we discussed earlier, there are various ways to accelerate remodeling by inducing a small amount of skin damage with a needle, laser or other means. This encourages the body to repair and rebuild the injured area.

Reducing Scars with SRCPs

SRCPS are skin renewal copper peptides that aid in the process of remodeling our complexion and removing scars. Here is how they work: SRCPs help activate your skin's metalloproteinases (enzymes that catalyze the splitting of proteins) that remove impaired proteins such as sun-damaged collagen, elastin and scars. At the same time they help activate your skin's anti-proteases TIMP-1 and TIMP-2 that protect against excessive breakdown of protein. (Simeon et al, Life Sciences, 15, 2257-2265, 2000). They also reduce the skin's protection of the scar-producing factor TGF-beta. Interestingly, retinoic acid (retin-A) is often promoted for remodeling skin and reducing scars. However, retinoic acid actually increases the production of the scar-producing TGF-beta. (McCormack, Nowak and Koch, Arch Plast Surg 3:28-32, 2001).

SRCPs work best with hydroxy acid such as salicylic acid. The hydroxy acid loosens the scar proteins and the Copper-Peptides help in the removal of the scar proteins. SRCPs also help the process of rebuilding new collagen and elastin into the skin. SRCPs help the skin to (1) regenerate new collagen and elastin which improve skin firmness and elasticity, (2) increase the production of water holding glycosaminoglycans which is true moisturization, (3) improve the skin’s blood vessel microcirculation, (4) produce biochemical energy from nutrients in the body’s blood supply, (5) increase the natural defense mechanism against oxidative damage, and (6) repair damage to the protective skin barrier. For scientific references on these effects see: Copper-Peptide Regeneration.

As the skin is rebuilt and scars removed, the elastic properties of the skin pull it into a smooth surface.

New Exfoliation Products – Salicylic Acid and Copper Salicylate

Not all hydroxy acids are created equal. Salicylic acid is a beta form of hydroxy acids called BHAs. Our SRCPs work especially well with beta hydroxys.

A leading dermatologist, Dr. Albert Kligman, believes that BHAs (in particular salicylic) at concentrations of about 2% are more effective than AHAs for anti-aging and skin exfoliation. Professor Kligman is well known for his research on the anti-aging actions of retinoic acid (Retin-A). Results from Dr. Kligman's laboratory found that the outermost stratum corneum layer is renewed after applications of salicylic acid.

Salicylic acid is also far more gentle than AHAs. Here's why: A small amount of the salicylic acid is converted into copper salicylate, a powerful and safe anti-inflammatory. This blend both exfoliates and soothes. In addition, this BHA may benefit those of us who enjoy the sun since salicylates absorbs ultraviolet light. Professor John Sorenson has researched and written extensively on beneficial actions of copper salicylate on skin, general health, and the anti-cancer properties of copper salicylates. See: www.skinbiology.com/copperhealth.html.

In conclusion: BHA hydroxy acids loosen damaged skin proteins while SRCPs help to remove them. This powerful synergy will put a hex on your scars.

 

 


 

Reducing Scars or Lesions with SRCPs and Salicylic Acid
System Advantages  Problems 
TriReduction used with Exfol Cream Reduces many small scars and lesions Stubborn resistant scars may need stronger hydroxy acids  
Super CP Serum or Super Cop - these are mixtures of SRCPs and Salicylic Acid Often quite effective May need to also use an additional hydroxy acid product
SRCP products in conjunction with 30% to 70% hydroxy acid peels Much more effective scar removal - any scar or lesion can be dissolved May cause burns and more scars 
Should be done by experienced dermatologist
Super CP Serum plus  Exfol Serum  Best on areas where acne is a problem Deep pitted acne scars may need needling to break up hard scars


If the SRCP and Hydroxy combo do not work fast enough, you may need stronger products

While stronger hydroxy acids will speed scar reduction, they may also irritate sensitive skin. We recently developed LacSal which contains 10% hydroxy acid. Although it is a bit stronger than our 2% Exfol cream, we have rarely witnessed irritation and many customers love the results. Some also are fans of our potent SRCPs with 30% to 70% hydroxy acids. These powerful SRCPs can produce striking results but may also irritate skin. Please slowly work up to these stronger products so your skin can adjust and use them under the direction of a dermatologist or esthetician.


Free Bonus Size when you spend $50
Items available include CP Serum and Exfol Serum, P&R Versions, Day Cover, Emu Oil Versions, P&R Suntanning Lotion, Folligen Lotion, Folligen Cream, TriReduction Scar Reduction Creams, Folligen Solution Therapy Spray, Protect & Restore Body Lotion Versions, Folligen Therapy Shampoo and Conditioner, Calypso's Oil Versions


TriReduction – Scar Reduction with Copper-Peptides, Retinol and Salicylic Acid

TriReduction creams are specifically formulated with strong Copper-Peptides that signal your skin to remove scars and repair itself. These powerful products use the combination of SRCPs, Retinol, and Beta Hydroxy Acid to diminish the appearance of scars, blemishes, and sun damage lesions.

Beta hydroxy acid exfoliating creams, and their more potent versions are used as "chemical peels" to remove upper skin layers. Likewise, Retinol and Retin-A (retinoic acid) both help to reduce scars and blemishes, but they often inflame the skin. Copper-Peptide creams help to reduce irritation and seem to enhance the benefits of Hydroxy Acids, Retinol, and Retin-A.



Exclusively from Skin Biology. These new and advanced Copper-Peptides for skin regeneration are available exclusively in Skin Biology products. Five US patents have been granted to Skin Biology for the exclusive use of this technology (US 5,698,184, US 5,382,431, 5,858,993, US 5,888,522, US 5,554,375) and more patent applications are pending.

Why Skin Biology's Copper-Peptides are Effective and Safest:

Skin Biology's new and patented SRCPs are, in Dr. Pickart's opinion, the most effective SRCP system to date. These breakdown-resistant, improved SRCPs give a longer-acting and stronger skin regeneration and also can be used with hydroxy acids and Retin-A. In contrast, the fragile peptides (tripeptides or pentapeptides) in many cosmetics are short-acting and cannot be used with hydroxy acids. Extensive safety testing has proven Skin Biology's SRCPs to be nonallergenic and none irritating. Skin Biology's products have neither the allergenic sensitization problems of the bacterial produced Copper-Peptides nor the biological inactivity of copper complexes ("colorless-copper") used by some cosmetic companies.

Rigorous testing by leading dermatologists: Skin Biology's skin repair products have been proven effective after rigorous testing by leading dermatologists. Clinical studies demonstrating the skin regeneration and anti-irritant actions of our products are published in international dermatology journals. No cosmetic skin renewal products on the market have this level of independent published evidence. Clinical and Safety Studies on Products


 

Comparison of Scar and Lesion Reduction Methods

Scar Reduction Method
Cost 
Advantages 
Time to Noticeable Improvement
Potential Complications 
SRCPs such as TriReduction or Super Cop $30 to $60 Low cost
Ease of use
One month
None
Glycolic acid 
Salicylic acid 
$30 to $60  Low cost
Ease of use
One month
Mild skin irritation 
Retinoic acid $100 to $300 
($50 to $100 products, 
$50 to $200 dermatologist appointment)
Low cost
Ease of use
One month
Skin irritation can be severe
Using both SRCPs and hydroxy acids  $30 to $60  Better results with less irritation than hydroxy acid alone  One month
None 
Mixtures of SRCPs,  
Salicylic acid, 
and retinoic acid 
Better results with less irritation than salicylic acid or retinoic acid alone  One month
Mild skin irritation 
Plastic sheets  $100 to $400 for plastic sheets plus 
$200 dermatologist appointment
No pain Two to four months 
Modest results - takes months
Scar Subcision or Needling $300 to $500 
dermatologist costs
Often works on severe localized scars or deep pitted acne scars.  Two to four months
Some estheticians use CP Serum after subcision and report a much improved result. 
Laser resurfacing  $1,000 to $4,000 Good with
skilled dermatologist
or esthetician
Two to four months
Painful
Local pigmentation 
More scarring 
Deep peels $500 to $3,000  Good with 
skilled dermatologist 
or esthetician
Two to four months
Painful
Local pigmentation 
More scarring 
Skin infection 
Dermabrasion  $1,000 to $3,000 Good with 
skilled dermatologist 
or esthetician - 
Sometimes good for deep scars 
Two to four months
Painful
Local pigmentation 
May have scarring or
skin infection 
Microdermabrasion  $200 Milder than dermabrasion but an "At-Home" method Two to four months
Milder than dermabrasion - 
Low cost 

 



   


 

SRCPs Activate the System that Removes Damaged Proteins and Scars from the Skin

During skin remodeling, the old damaged protein is removed and replaced with new collagen and elastin fibers. This removes scar tissue, restores skin elasticity, and reduces wrinkles.

SRCPs help activate the skin's scar-removal system. The removal of scars and damaged skin proteins involves complex interactions between the metalloproteinases, a family of at least 14 proteins that remove damaged proteins such as sun-damaged collagen and elastin, and the TIMPs, proteins that inhibit metalloproteinase actions so that healthy tissue is not damaged during the scar removal process. SRCPs stimulate the production of certain metalloproteinases while inhibiting others by increasing the production of the proteins TIMP-1 and TIMP-2 that inhibit excessive and potential damaging actions of metalloproteinases. (Maquart et al 1999, Simeon et al 1999, Simeon et al 2000)

SRCPs Reduce the Scar-Producing Factor, TGF-beta

SRCPs also reduce fibroblast secretion of TGF-beta (transforming growth factor beta-1). This effect occurs with normal fibroblasts and keloid-producing fibroblasts. TGF-beta-1 is a growth factor that increases wound healing but also induces scar formation. This, combined with the healing actions of SRCPs, suggests that scar-free physiological healing needs both an activation of metalloproteinases plus a reduction in TGF-beta-1 production. (McCormack et al, 2001).


   

Product Ingredients - See ingredients
 

 

 



Product Reviews:


I've been using the Copper Peptide Serum for approximately two months ....Within the past couple of weeks, I've seen incredible results - both visible and tangible! I've tried countless products in an attempt to address my post-acne problems, but SRCPs have proven that I can remedy them using the 'remodeling power of my own skin!' ...

This is just one example I cannot help but share: I had tried to heal hypertrophic scarring I had along my jawline. SRCPs had removed them entirely. Not only do I feel more confident about their removal, but I no longer experience the intense itching associated with their presence. I used to go to the doctors to get injections directly into the lesions -- very painful and expensive AND they still persisted!! They even persisted AFTER I visited another doctor to get pulsed-dye laser treatments done!! I would avoid touching my jaw area because they were so discomforting... now I must get used to touching the smooth, healthy skin!! It's such a relief. I couldn't have imagined that my skin itself could be encouraged to remove the damage.

I have so many positive things to state about SRCPs -- so many more things that it's probably not a good idea to keep rambling on! It has given me a renewed hope about gaining control of my skin... of returning it to the state before I had my unfortunate bouts of acne. I was once considering getting more laser treatments for my scarring. I don't think so any more. I don't have to spend millions on questionable procedures or risk further damage to my skin. I cannot wait to see the improvements a month, two months, three months from now. This is truly the greatest investment I could have made, and I thank Dr. Pickart for bringing us such a marvelous product. SRCPs are nothing short of miraculous. Not only have they improved my skin quality, but they have given me a significant boost in self-esteem -- that is golden.

-R.O.


I had a biopsy scar on my neck (in that triangle where the neck meets the collarbone and the shoulder muscle attaches - I have a nice neck, so all my shirts showed this area off to it's best advantage, so it was REAL obvious). It was about as large as a dime.

Without using the SCRP's on it, it had stabilized in about 3 months. It was red (I have scars that are still red after years), the walls on the side were vertical, it was much lower than the rest of the skin, and it was very noticeable.

I started using Exfol Serum on it, then immediately plopping Super CP Serum on it (one full drop from the bottle originally filled the scar indentation - it was pretty large).

Well the edges are sloped now, the bottom of the scar is rising, and it's pink, not red. The skin in the middle of the scar is even with the non-scarred surrounding skin. A nice bonus - since I'm not terribly careful about where I plop the stuff, there's a surrounding area of skin that is FANTASTIC, and the freckles that were there have faded, some have even disappeared (I did not like my freckles)!!!!

I use it twice a day when I remember, which isn't as often as I should. When I put it on, I'll also pinch the skin between my thumb and pointer finger and gently rub - one of my friends who's a massage therapist and works with people who've had car accidents says that helps break up scar tissue a little, but very gently.

I'm super thrilled, and just wish I could upgrade to SuperCop 2X...

I wish I'd taken before pictures now, but I didn't terribly want a reminder of the scary skin cancer biopsy stuff. If the scar is completely gone by the time I'm done, I will actually be glad to have no reminders of that horrible time. Yay!

-MBP


I've been surfing for 20 years and due to sun damage I had extensive hypopigmentation. I started with Exfol Cream, Protect & Restore, and Super CP Serum...At the beginning I did 40% lactic acid peels done once a week, to supplement my regimen of Skin Biology products (eventually I was able to slowly work up to 65% lactic acid once a week)...But it was after only six weeks that I started to notice an improvement - a sort of 'breaking up' of the hypopigmentation...Now months have passed and I'm seeing excellent results...

I would also remind people working with hypopigmentation to remember to use some type of sun protection when they go out, since the skin can hypopigment again and all your progress can be un-done because of un-protected sun exposure. Also the lactic acid has been the most successful hydroxy acid for me. Even with my sensitive skin I can use it and the Super CP Serum and after trying so many things for hypopigmentation I've finally started to notice a visible difference! Thank you.


I did something a little nutty to test the products. I took an eyebrow brush and brushed a deep line/wrinkle on my neck vigorously. It turned very red but did not bleed. Than I treated it with Exfol Serum every morning and Super Cop every night. After only 2 weeks I noticed it is 50% less visible. I am happy with that!

U.A.


Well it's been, I would say, 2 months since I started using Super Cop 2X and 5% BHA. I was suffering from ingrown hairs, pitted acne scars, large pores, and my face was sort of dull looking. Well the results are amazing!!!

My pores are all gone and after I shave my face the next day I don't get ingrown hairs or those little bumps any more. My scars were ranging in size from deep to sort of like needle pricks well the little ones are all gone and the deep ones are filling in (about 60%) . Now I know people out there who say "I'm not getting any results I'm going to stop using this and just move on to something else". But let me tell you I have tried almost every single product on the market (you name it and I've tried it). The only thing is that these products work slow, but they do work.

So don't give up cause right when I was about to give up, my cousin was like, "What happened to your skin? You don't have those scars you used to?" Cause I see my face everyday and I can't really see the small changes that are happening but after my cousin made that comment, I went and got some old pictures of me and compared to what I saw in the mirror and was shocked how dramatic my face had changed in 2 months.

My method was very simple. In the morning, wash face with Dove Bar or 2% BHA then apply 5% BHA. Then in the evening do the same thing. Then at night wash my face with the 2% BHA then apply Super Cop 2X. I don't use any peels or anything else (too time consuming). The way I feel is that the easier your method is, the more you will do it and not slack off, therefore you get better results.

-T.G.


Dear Skin Biology, I just wished to thank you for your excellent products. I have been using copper-peptides for about 7 weeks now, for the last few weeks I have been using Super Cop 2X, putting it on my acne scars with a small metal spatula (actually a tool from a manicure set!). For exfoliation I have been using Exfol Cream and a dermabrasion cloth. For the last week I have been using the dermaroller.

The effect on my skin and in particular upon my scars is amazing. My scars have improved so much I no longer need to wear make up. And from being quite noticeable on both cheeks you now have to peer hard to see them. Thank you so much. I shall be building my collection of Skin Biology products as and when I can.

-N.A., Scotland


I just wanted to thank you, Dr. Pickart, for all your hard work and lifelong dedication of applying chemistry to help people. I have been using Skin Biology products for 2.5 months and have seen a huge improvement in my acne scars. I have suffered from acne as a teen and finally cleared up at around age 23. But had scars on cheeks, jawline, and side of temples. Makeup always drew attention towards my scars and I have always been ashamed of them. I tried the dermatologist thing, was signed up to get fraxel lasering (which I was really apprehensive about doing because it may cause more damage than good) and cost $900 a treatment and I was going to need 4-5 treatments.

Then I found your company and starting using the Acne Scar Reduction Kit. It seemed a bit slow at first, but I used the products everyday and never had any irritation. After testing the starter kit, I used the Exfol Cream and TriReduction with Retinol and spot treated with Super Cop 2X. After a month, I started using 40% lactic acid and 15% fruit acid gel in place of the Exfol Cream, still using the TriReduction with Retinol and Super Cop 2X. While I didn't expect overnight success or complete irradication of the scar tissue, I did get what I expected after 3 months:

My overall skin tone is bright, many scars have gotten smaller, less red, and the indented scar areas I had have become more even level with the rest of the skin, and I have a more even skin tone. My acne scars are truly less noticeable and I am comfortable with my skin now and feel really good about myself every time I examine my skin in the mirror.

I just wanted to take the time to thank you for all your help and for offering these products at a reasonable price. I would have spent a kabillion more dollars with fraxel lasering and no telling what I would have gotten. I am going to continue using the products for a long time and I have also tried the Folligen Cream on my eyelashes, and wow they have grown fuller and longer and they look good.

Thank you so much, I feel very blessed to have found your products.

-L.C.


Firstly, I just wanted to say how amazed I am at the products ...I was involved in an attack 3 years ago where I was robbed and severely beaten and had many scars on my face ...After reading your web site, I thought I will have a go at your products...Got the Super CP Serum and the 2x copper cream stuff [Super Cop 2X - Extra Strength].

My god the scars have all gone and my skin is so clear and firm looks like it used to. I worked as a personal trainer for many years and looked after my skin. It's now at its best...it's really firmed up. It's fresh and blemish free, and to think that I had such marks on it from the attack - it's a miracle. I will be spreading the word. You really have helped me so much. From the bottom of my heart, Thank You!!

I'd be happy if you used my name if you wanted in your web site to recommend the products as I would tell everyone to use them...

2nd Email Received:

Just to let you know the way I used it:

I used glycolic acid on alternate nights with some salicylic...then applied my serum all over. Then a nice layer of the cream over the top in the areas that needed extra help. You could see where I put the cream as I placed it in lines over my scars. OK, it tingled but what the hell ...every morning when I washed my face the scars were less and less, I was so amazed. And if you were to see my skin now you would think I never had a problem ever. In fact you would think I was 10 years younger than I am. I had a facial, and the woman doing it thought I was 24 (in fact in 35) but my skin is firm and totally smooth and clear as anything. I also use the Emu Oil - Wow what amazing stuff...the ingredients you put in it are really good.

All in all you make the best stuff and I've got all my personal training clients using it too. So I will spread the word.

Thank you - And I mean that.

Daniel Saville,
Yorkshire, England


Just wanted to share this little story. I've had an annoying calcium deposit on the side of my nose for 4 years. When a second one appeared on the other side I had already read all your feedback about peeling and peptides (P&P) getting rid of other weird skin things and decided to try it on these two calcium deposits.

I read your new piece wherein you describe how animals scratch and pick and abrade and decided that that was the only way to really ensure the peptides were absorbed into these things. So I peeled with acids (light, alpha or beta) and I put the gold 2x [Super Cop 2X - Extra Strength] on it, a big glob, at night. I waited some time and then added the Emu Oil to aid penetration.

This was a bit irritating to the skin over these things - and it kind of scabbed up after a couple of days, which I've learned is a good thing with the peptides. I read that you're telling people less is more now, but in my case that irritation followed by more peptides which is followed by a scab is the process that gives me the greatest results! Of course I only do that in spots: target ONE bad wrinkle, for example, scratch it, peptide it, wash it, peel it, peptide it, pick it... etc.

Using this target P&P approach with the worst and oldest wrinkle, I worked on it for weeks and weeks, worried I was making it worse by irritating it. Then one day I picked at the scab that had formed over it and -oh my god - the wrinkle had filled in! This thing was older than the hills and a dermatologist had told me it was so deep even laser surgery probably couldn't get to it! No... Dr., but copper peptides can.

-L.B.


After spot treating my age spot with 10% glycolic acid and SRCPs for two months and reading about some chemical peel procedures, I got inspired to improvise a spot treatment using corn/callous remover to remove my sun spot on my cheek. It took a leap of faith to experiment strong acid on my face because I only use Exfol Serum (2% salicylic acid) in my regular skin care regimen. The 10% glycolic acid is used only to spot treat the sun spot.

It took only three applications of 12.6% salicylic acid or 1.5 days to peel and reveal the healthy pink skin underneath. I have no raised or pitted scar. I am so happy. Today is the 7th day, and I am dealing with only a slight post inflammatory hyperpigmentation. Soy salicylic acid cleansers/Exfol/SRCPs/BHOs and vitamin E oil regimen gives me a wonderful even skin complexion and smooth skin texture...

THE CORN/CALLOUS REMOVER METHOD

DAY 1:

* Facial skin is delicate so use strong acids with extra caution.
* Read and follow directions on the bottle.

AM: Cleanse, steam face (soften and prep face to receive salicylic acid), and test corn/callous remover on face.
-Moisten and prep a Q-tip swab with glycolic toner (or alcohol).
-Drop one small drop of Dr. Scholl’s Corn/Callous Remover on the Q-tip.
-Dot the age spot with the Q-tip with the Corn/Callous Remover. It’s normal to feel some sting.
-Let dry. A leave-on product.

PM: Repeat a second time at night if there is no unusual severe reaction (no need to steam your face this time).
-Use the same swab and repeat the procedure to apply the salicylic acid on the age spot.
-Due to some discoloration, you may want to cover the treated spot with a band-aid if you are going out in public places. You could cut up the band-aid to custom fit the size of your age spot. Without the skin peeling, the band-aid is just for cosmetic cover at this point.

DAY 2:

AM: Cleanse face as usual and apply corn/callous remover as before. Use the same swab and repeat the procedure to apply the salicylic acid on the age spot (no need to steam face if it’s done after a shower). Your age spot may peel in the morning without another application. I had to apply another treatment of corn/callous remover, and I peeled in the afternoon.

PM: The pigmented layer should have melted and come off easily without pulling or scraping. I didn't need to steam my face to peel the pigmented dead skin layer, but you could also steam your face to help removing it. Remove the dead skin layer lightly and carefully with little pulling or scraping to prevent scarring. You’ll see a healthy but a pink skin layer.
-Apply Neosporin.
-Band-aid the raw spot if you are going out. I cut out and used only the clear part of the band-aid strip to cover the open lesion (two layers) to match my flesh color. Two clear taped layers for some UV protection and so I can camouflage the taped lesion with cosmetics.

DAY 3:

AM and PM: Cleanse and moisturize the raw spot with Emu Oil only. No acids and copper peptides.

DAY 4:

AM:
-Lesion looked healthy and evenly pink.
-Lightly buff off any pigmented tissue fragments with a dry wash towel.
-Cleanse and apply CP Serum (first day using copper peptides after the removal).
-Moisturize the face and the removed lesion with JASON Vitamin E Pure Beauty Oil (first day using vitamin E oil).

PM: Repeat as AM. You could replace CP Serum or spot treat with SC-2x (or Super Cop) for more precise application.

DAY 5-6: Treat exposed healthy skin with SRCPs and Emu Oil-S/vitamin E oil. Super CP and Super Cop okay but no exfoliation until the 7th day for me.

-J.W.


THANK YOU!!!!!!!!!!

I have been a fan and committed user of Skin Biology's Copper-Peptides for about 18 months. Initially I noticed an improvement in skin quality and moisture content when I commenced using CP Serum for acne scarring, burns from a CO2 laser and scar revision surgeries (post car accident).

Within approximately 2 months, scars began to look somewhat improved. At that point I switched to Super CP Serum (in conjunction with a 2% BHA). By the 16 month mark, due to continued once-a-day use, the rolling acne scars, large pores and some chicken pox marks had noticeably improved, although I was still "filling in" the ice-picks (now significantly smaller) with heavy make-up.

At the beginning of this year, you were kind enough to let me try the SuperCop 2X [Extra Strength].

I AM COMPELLED TO REPORT EXTRAORDINARY RESULTS.

After just one month, I defy anyone to recognize a sufferer of cystic acne (my scars were thirty years old!), I no longer "fill" any ice-pick scars (they've disappeared), where I'd sustained tissue loss from the car accident (filled-in as well), chicken-pox scars (don't recall exactly where they were)and at almost 49 years of age, am totally wrinkle-free. That alone is a feat, since I was one of those kids the docs in the '70s recommended sun-lamps to as therapy for acne.

My gratitude is enormous - and I know of which I speak since historically I have tried (with limited success)everything on the market, including but not limited to, dermabrasion, 2 physician administered chemical peels, scar revision surgeries, laser resurfacing, A, C, ALA, DMAE and so forth.

And furthermore, unlike all of these other 'therapies', there is no drying, inflammation, swelling (which can appear to diminish scarring - in the very short term), or irritation of any kind.

Hence - I will continue to use the SuperCop 2X, since in addition to all of the previously mentioned benefits, my skin has never looked or felt healthier. No other product is required.

-N.I.


When Skin Biology says that their products heal and renew skin: THEY REALLY MEAN IT. I had to have steroid injections injected to the outside of my nose due to a reaction to surgery. I had huge unsightly lumps and needle marks all over my nose. The scar tissue looked like large warts. I was embarrassed to go anywhere. I consulted other physicians who told me that the only way to remove the extensive damage was through skin grafts and more surgery. I emailed Dr. Pickart after finding this site during a search. He was so confident in his products. I had to give it a try.

He saved me from surgery!!! After just 2 months of using Exfol, Super Cop, and TriReduction, the areas that were damaged raised, peeled off - and the remodeling has begun. I also had very deep wrinkles on one side of my nose...They are almost gone.

My husband keeps checking the area in various light conditions because he cannot believe that not only has the appearance just improved, but the damage is almost all gone...

The other benefit is the tightening of my skin all over my face. Reduced puffiness in the a.m. around my eyes, and a fuller overall look to the skin.

I could go on and on because I really did get to skip surgery because of these products...Good luck - you'll love the results if you hang in there- it's worth it.

...I bet my surgeon would like to get his hands on these products.

N.N.


I MUST say that even though it's only been a little under two weeks, Skin Biology products are without a doubt the best things I've ever put on my skin!

Not only is my face looking a little better...but, even better, the little skin tags I had on my neck are gone! Just from using Tri-reduction! I had read somewhere on the board that someone had gotten rid of them using SuperCop, but since I couldn't get the SuperCop I thought I'd try the Tri-reduction. I used it twice a day, with Exfol and also a drop of Super CP Serum, all rubbed vigorously in the proper order into the tags. The places got very irritated and scabbed a little, but I kept on. The largest one I had (not very big, about 1/3 of the size of a small kernel of corn) just "exfoliated" away tonight. Rubbed right off as I was washing my face & neck!

I'm so happy about this I can't say ...I never had any of these things until about five years ago, and even though I didn't have very many at all I HATED them profoundly. Several really tiny ones came off in the last several days, but the one tonight was the biggest, and the main "target." I had even planned to have it cut off after I got out of school, but thanks to Dr. Pickart and Skin Biology I won't have to! I'm convinced.

A.L.


I can share this experience. I have from time to time developed HUGE cyst-like zits that I had to have injected with steroid shots. One of the side of effects is fat atrophy (aka, a big pit in your face!) They naturally fill in - in 4 to 6 months! Well, I started filling the holes in with Copper Serum (just put a big glob right in the pit) and they filled right in within a month. Also, the research shows SRCPs do increase fat under the skin, so I'm thinking these products can do nothing but help.

K.L.


When I first started using the TriRed[uction]. I immediately had two of my 4 skin tags on my neck get crusty and fall off...that sure convinced me that these products work and work well.

S.I.


Thank you for your Super Cop 2X [Extra Strength] - which I am using. It does tingle but I don't mind as I feel it is working! I also use P&R Cream 3 [Protect & Restore with Retinol] in the morning and Exfol Cream at night (interspersed with Super Cop.) I sometimes put Emu Oil on top of the Super Cop 2X...

I am 61 but look 48-ish - even the American customs/security people at the airport last week checked my age. And at hospitals, they check they have the right person(!)...I have been using your products for some several years now and they are my total lifeline. I could never contemplate using anything else.

Regards,

-A.M.


Progress of Scar Reduction:

**December 7, 2004
(Client started using Exfol Serum and TriReduction Cream for scar reduction.)

"I'm pretty anxious to escape my scar tissue prison."

**December 30, 2004

"I've been using TriReduction for three weeks now. There is no blatantly obvious success as of yet, which is kind of a bummer, because people on the net are writing their scars have flattened in three weeks using your TriReduction."

**January 3, 2005

"The itching is now almost gone. So I guess I'm just gonna continue smearing what I have now. I wasn't using a lot in the first place."

**January 22, 2005

"I just wanted to let you know that I've been smearing for more than 6 weeks now, and I can definitely tell the stuff is working for me.

The scar has flattened a little, and the back of my head feels a lot more normal now. It no longer itches and ........is becoming more pinkish. It used to be bright white.

After 6 weeks of use, the itching, that I got at first from the CP's, is now almost completely gone. I hope this will accelerate the healing process even more. Because boy oh boy am I looking forward to yet MORE results another 6 weeks from now."
- Submitted


I am amazed at how this stuff doesn't irritate my skin being the strongest product [comment on Super Cop 2X - Extra Strength]. I just cleansed and put it all over my face/neck...As you only need a little...my skin sucked it up and I swear my pore size has diminished heaps...The Super Cop 2X is fantastic.

M.Y.


I have been a Dermatology Nurse for 12 years and never have I seen results as quickly as I have with the products that I have tried so far...With so many dermatological issues out there I am beginning to be more convinced that you have a product for just about everything ...Thank you.

B.W.


I want to thank you for all the helpful information provided on your site in addition to your wonderful products. I've been on the Super Cop Cream alternating with the TriReduction and Emu Oil-S for several months now. I also use Retin-A a few times a week. I recently did some glycolic peels just on the skin damaged area once a week to speed up the results and that area on my face keeps getting better. I thought I would have to live with my skin the way it was before (uneven texture and hypopigmented from a burn) but I'm determined to have beautiful skin again. The smoothness of my skin and return to healthy skin is so great to witness. Thank you Dr. Pickart and your helpful staff, your products are incredible. I'm thrilled with the results on my skin!
God Bless.

S.L.


Just wanted to let everyone here know that I am very pleased with TriReduction P&R with Retinol. I graduated to TriRed [TriReduction Protect & Restore Cream] after a year of using P&R 3 [Protect & Restore with retinol]...and CP/Exfol Serum. My skin tone shows a demonstrable improvement after 2 weeks us of TriRed.

R.V.


Update: I have 'mature' skin ...I am 52. I have been using Skin Bio products since last May and worked up from CP Serum to Super CP serum on my face, neck and upper arms in the late fall ...I believe that the texture of my face and neck has greatly improved. I LOVE the Super CP Serum and my skin seems to tolerate it well. The Squalane with Retinol is the best overall moisturizer that I have ever used on my face, and my face feels much softer than it has been in years...Eyes: the skin under my eyes is still going through some remodeling, but it has improved from where it was when I started and I continue to see improvements. Neck: I have "neck creases" that I have had all my life, but of course look worse with age. I believe that the combo of the Skin Bio products that I use has helped the overall appearance of my neck a lot.

K.C.


I have just started using the Super CP Serum on my stretch marks and my face ...I use a few drops of CP Serum and mix it with a Royal Chiffon Cream I bought from 30glycolics.com, and Wow! in ONE DAY my boyfriend told me my face looked 'glowing', and he didn't know I was using it!...I really did notice a difference, myself, too.

P.


I have read your research findings on Copper Serum [Skin Remodeling Copper-Peptides], and I am sold on Super Cop! Not just for stretch marks, but for my face and body as well. I have been a life-long 'health nut' since age 10, too, so I appreciate the information you have for us to read. I have just begun, and I'm using the Super CP along with other products in a daily/weekly regimen, for about a month now. I think of using one or 2 different white-colored moisturizers, (sometimes 100% aloe gel too later on) mixed in with or on top of Super CP Serum it eliminates staining, which can sometimes make a scar look worse than it is. At least this worked for me. I understand it takes time, so patience and persistence will be my guide as you said.

P.C.


I'm 48 years old with sun damaged skin. My skin is so smooth and vibrant. My eyes are so firm and smooth, YAY! I don't have any dead skin cells. I started out slowly and only used the Squalane Lipid Replenisher as my moisturizer for my face and eyes. I love the moisture and texture of this squalane, nice and light. YAY! But overall I really loved and enjoyed these samples, my face is pretty and I don't need alot of makeup, it's like I just have a natural beauty look. Okay, I used the Super Cop only on my acne scars at night and nothing over it and they have lightened up dramatically. YAY! for that too.

M.H.



"I only started CP products a year and a half ago. I had a Chemical Peel (TCA, medium-depth) a year prior to starting the CP Serum. What do you want to achieve? I had very visible acne scars on both cheeks. My scars are nearly gone now. In fact when I point them out to people who haven't seen me previously with the scars say they cant see any. I'm very, very pleased."

M.



Most Unexpected Comment on TriReduction:

I also wanted to say that I've been using the Tri-Reduction cream on my gums because I had a little gum recession problem and they were bleeding a bit when I brushed, and I figured maybe it'd work, and it did. My gums look great and don't bleed anymore (can't recommend the taste, but I don't swallow it either). Thanks for the great products!
N @earthlink.net


"The Turn Back the Clock Doc", Loren Pickart has spent his life working on methods to reverse the effects of aging in the human body. He is the discoverer of the role of remodeling copper peptides on the repair of human skin and other tissues such bone, hair follicles, liver, stomach lining, and the intestinal tract after his isolation of the human skin remodeling copper-peptide, GHK-Copper from human blood. Skin remodeling copper peptides are the body's natural signals that repair and restore damaged and aged tissue by (1) inducing strong anti-inflammatory actions (activate superoxide dismutase and decrease damaging actions of TGF-beta and interleukin-1), by (2) stimulating the removal of damaged and older skin by increasing the synthesis of metalloproteinases, and (3) by increasing the generation of new collagen, elastin, proteoglycans, and rebuilding the microcirculation and by increasing production of new skin cells. He and his wife, Charlene, worked to start ProCyte Corporation in 1985 to develop his first generation of GHK-Copper products and Skin Biology in 1994 to create a second generation of more effective, skin remodeling copper peptides.

Products based on Dr. Pickart's inventions are using skin renewal, improving hair growth, increasing the success of hair transplants, and after dermatological peels, laser resurfacing, and dermabrasion by many companies including AdviCare, American Crew, Amuchina (Europe), Atelier Esthetique, Bard Medical, BioPharm, Creative Nail Design, Johnson & Johnson, Schering AG, Neutrogena, Osmotics, ProCyte, Sigmacon Medical Products and Tanox Biosystems.

 

 

Skin Biology is on a quest to renew and rebuild your skin, to turn back the clock on skin aging. The key is to tap into the SKIN RENEWAL CYCLE: the first explanation for how the skin repairs itself. Dr. Loren Pickart, the biochemist who originated this ground-breaking theory, is famous for his discovery of skin remodeling copper peptides which are integral to the cycle of skin renewal. 

Dr. Pickart designs our products based on his scientific inventions in biochemistry and cell biology rather than on hocus bogus science that promises hyped hope in a jar. Our mission is to develop safe and effective products that activate your skin's natural renewal systems. Skin Biology products assist to remove the effects of aging and damage by restoring skin and hair to a younger and healthier condition.

Dr. Pickart has spent over 40 years developing methods to repair and regenerate various tissues of the body. His inventions have been confirmed by independent, published studies from over 40 universities and research centers. His discoveries have been proven to:

Calm irritated and reddened skin
Tighten loose skin and improve elasticity
Increase skin elasticity
Thicken older skin
Tighten the protective skin barrier proteins
Improve skin firmness
Reduce fine lines and depth of wrinkles
Act as powerful anti-inflammatories on skin
Improve skin clarity and “glow”
Reduce spots, photodamage, and hyperpigmentation
Smooth rough skin
Improve overall appearance
Improve hair transplant success
Improve hair growth and thickness
Restore liver after toxic poisoning
Block stomach ulcer development
Heal intestinal ulcers
Accelerate wound healing
Cause the differentiation of stem cells
Increase the production of stem cells
Protect skin keratinocytes from UV damage by inactivating reactive carbonyl species

No researcher, or cosmetic company, working on skin has this depth of independent, published confirmation on such a variety of inventions and fundamental discoveries on tissue renewal and regeneration. For more details and references see: Tissue Remodeling Copper Peptides

Latest View of Skin Remodeling Copper-Peptides
Published Research on Positive Effects of Skin Remodeling Copper-Peptides
Book: Reverse Skin Aging — Using Your Skin's Natural Power

ORDER NOW

 

 

Skin Biology is currently patenting and test marketing various products built around his new skin remodeling copper-peptides that are designed to possess greatly enhanced potency, strong breakdown resistance (and can be used with skin exfoliating hydroxy acids for more rapid skin renewal and for scar reduction), a longer duration of action, and very high adherence to skin. The first generation products designed around GHK-Copper performed well in many controlled tests; however, they failed in FDA clinical trials on the healing of difficult-to-heal human wounds. Dr. Pickart is of the opinion that this second generation of copper peptides should have a higher chance of success in difficult clinical trials.

Pickart currently is working on a theory of the biochemical mechanism of how the human body repairs damaged tissues and organs.
   

 

Dr. Pickart's Recent Articles 
"Formula of Love", Cosmetics &
Medicine (Russia), May 2005
"Improving Hair Growth with Skin Remodeling Copper Peptides ", Cosmetics & Medicine (Russia), July 2004
"Skin Remodeling with Copper Peptides", Cosmetics & Medicine (Russia), April 2004
"The Turn Back the Clock Doc", February 2004
"Copperceuticals and the Skin", Cosmetics & Toiletries, (USA) July 2003
"Reversing Skin Aging" in Body Language Dermatology (U.K.), April 2003 - with Before and After Ultrasound Pictures
"Copper Peptides for Tissue Regeneration" in Specialty Chemicals (U.K.), Oct. 2002

New: Special Skin Problems of Models, Actresses, & Actors

New: Removing Wrinkles and Why Wrinkles Develop

New: Tightening loose and sagging skin

New - Your Skin's Natural Skin Regenerators


 
 


 


 

The Skin Renewal Cycle

The following diagram is based on GHK-copper(II) actions. See Copper Peptide Regeneration for references. Newer Skin Biology skin remodeling copper peptides act similarly but are composed of less fragile peptides that also have a better adherence to the skin.
 

GHK Module




References

Maquart FX; Simeon A; Pasco S; Monboisse JC
Regulation de l'activite cellulaire par la matrice extracelulaire: le concept de matrikines,
J Soc Biol 1999;193(4-5):423-8

Simeon et al 1999 - Simeon, Monier, Emonard, Gillery, Birembaut, Homebeck and Maquart, Expression and activation of matrix metalloproteinases in wounds: Modulation by the tripeptide-copper complex glycyl-l-histidyl-l-lysine-cu2+, J. Invest. Dermat. 112: 957-964.

Simeon et al 2000
Simeon, Emonard, Hornebeck & Maquart
The tripeptide-copper complex GHK-Cu stimulates matrix metalloproteinases 2 expression by fibroblast cultures
Life Sci 2000 Sep 22;67(18):2257-65

McCormack et al, 2001 - McCormack, M., Nowak KC, Koch, J
The effect of copper tripeptide and tretinoin on growth factor production in a serum-free fibroblast model., Arch Facial Plast Surg 2001; 3: 28-32



Iamin Gel Wound Dressing®, Iamin Impregnated Gauze Dressing®, OsmoCyte® PCA Pillow, Iamin Wet Dressing (copper-saline)®, Iamin-2 Hydrating Gel®, Complex Cu3®, Iamin-Vet® GraftCyte®, and Tricomin® are trademarks of ProCyte Corporation and and marketed by ProCyte and Bard Medical. Blue Copper Firming Elasticity Repair®  and  Climate Extreme Body Repair with Copper Peptide® are products and trademarks of Osmotics Inc.


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